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THE MORE YOU KNOW
Chamomile
It exhibits antihistaminic effect. Animal experimental studies showed that en-yen dicycloether fraction of the essential oil of chamomile inhibits the release of histamine from the protamine sulphate-provoked degranulation of mast cells, which is the cause of allergic symptoms (102).

Chamomile extract has been found to exert anti-inflammatory activity in vivo, and so it is used for the treatment of inflammatory skin diseases.
Its activity is due to the Chamazulene component of the extract, which inhibits the formation of leukotriene B-4 in neutrophilic granulocytes and additional antioxidative effect lead to blocking the chemical peroxidation of arachidonic acid (103).

It has also been proved by experimental studies that chamomile extract demonstrated clear antidermatophytic activity (104).

Animal experimental study showed that a long-term exposure to low doses of the heteropolysaccharides from chamomile flowers enhance the immune response to bacterial infection and it has been concluded that chamomile extract has the ability to modulate the immune system (105). From the essential oil components: alpha-bisabolol and Chamazulene has the strongest activity on Gram-positive and Gram-negative bacteria and on pathogenic fungi (106).


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